Efficacy of antidepressants

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چکیده

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منابع مشابه

Efficacy of antidepressants in adults.

http://bmj.com/cgi/content/full/331/7509/155 Updated information and services can be found at: These include: Data supplement http://bmj.com/cgi/content/full/331/7509/155/DC1 "References w1 w20" References http://bmj.com/cgi/content/full/331/7509/155#otherarticles 3 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/331/7509/155#BIBL This article cites 15...

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Efficacy of antidepressants: similar but different.

Fountoulakis & Moller (2010) have re-analysed the Kirsch et al. (2008) meta-analysis of newer antidepressants and reached quite different conclusions to the original study. In particular they highlight that both venlafaxine and paroxetine exceed the NICE criteria for ‘clinical significance’ of 3 points on the Hamilton Rating Scale for Depression (HAMD) and that the Kirsch et al. analysis undere...

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Which antidepressants have demonstrated superior efficacy ?

A review of published evidence of superior efficacy of a particular antidepressant in major depressive disorder may assist clinicians in making considered treatment choices. To identify such candidates, an international group of experts met to assess published evidence (identified through searches in Medline and Embase databases and discussions with experts in the field) from randomized, contro...

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The Efficacy of N-Acetyl-Cysteine (NAC) Supplementation in FST Model for Screening Antidepressants

Introduction: The model for screening antidepressant-like activity in pre-clinical drug studies include, rat forced swimming test (FST). The reports on N-acetylcysteine (NAC) as an antioxidant supplement in stress related disorder is well documented. This study was aimed at potential antidepressant mechanism of N- Acetyl Cysteine (NAC), a glutamate precursor on FST animal model for screening an...

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Efficacy and effectiveness of antidepressants: current status of research.

BACKGROUND This paper examines the current status of research on the efficacy and effectiveness of antidepressants. METHODS This paper reviews four meta-analyses of efficacy trials submitted to America's Food and Drug Administration (FDA) and analyzes STAR*D (Sequenced Treatment Alternatives to Relieve Depression), the largest antidepressant effectiveness trial ever conducted. RESULTS Meta-...

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ژورنال

عنوان ژورنال: BMJ

سال: 2008

ISSN: 0959-8138,1756-1833

DOI: 10.1136/bmj.39510.531597.80